IRF6

IRF6
Identifiers
Aliases	IRF6, LPS, OFC6, PIT, PPS, PPS1, VWS, VWS1, interferon regulatory factor 6
External IDs	OMIM: 607199; MGI: 1859211; HomoloGene: 4479; GeneCards: IRF6; OMA:IRF6 - orthologs
Gene location (Human)
Chr.	Chromosome 1 (human)
End	209,806,175 bp
Gene location (Mouse)
Chr.	Chromosome 1 (mouse)
End	192,854,331 bp
RNA expression pattern
	Top expressed in
	secondary oocyte; ; skin of thigh; ; gingival epithelium; ; skin of abdomen; ; skin of hip; ; pancreatic ductal cell; ; hair follicle; ; skin of arm; ; olfactory zone of nasal mucosa; ; mucosa of ileum;
	Top expressed in
	corneal stroma; ; conjunctival fornix; ; Paneth cell; ; epidermis; ; urothelium; ; hair follicle; ; transitional epithelium of urinary bladder; ; epithelium of stomach; ; skin of back; ; ileum;
	More reference expression data
	n/a
Gene ontology
Molecular function	DNA binding; DNA-binding transcription factor activity; protein binding; DNA-binding transcription activator activity, RNA polymerase II-specific; sequence-specific DNA binding; DNA-binding transcription factor activity, RNA polymerase II-specific;
Cellular component	cytoplasm; extracellular exosome; nucleus; cytosol; cell junction;
Biological process	cell differentiation; regulation of transcription, DNA-templated; cell development; interferon-gamma-mediated signaling pathway; transcription, DNA-templated; mammary gland epithelial cell differentiation; keratinocyte differentiation; positive regulation of transcription, DNA-templated; keratinocyte proliferation; type I interferon signaling pathway; skin development; negative regulation of cell population proliferation; transcription by RNA polymerase II; positive regulation of transcription by RNA polymerase II; immune system process; roof of mouth development;
	Sources:Amigo / QuickGO
Orthologs
	3664
	54139
	ENSG00000117595
	ENSMUSG00000026638
	O14896
	P97431
	NM_006147; NM_001206696
	NM_016851; NM_178083
	NP_001193625; NP_006138
	NP_058547
	Wikidata
View/Edit Human	View/Edit Mouse

Interferon regulatory factor 6 also known as IRF6 is a protein that in humans is encoded by the IRF6 gene.