IRX2

IRX2
Identifiers
Aliases	IRX2, IRXA2, iroquois homeobox 2
External IDs	OMIM: 606198; MGI: 1197526; HomoloGene: 56490; GeneCards: IRX2; OMA:IRX2 - orthologs
Gene location (Human)
Chr.	Chromosome 5 (human)
End	2,751,677 bp
Gene location (Mouse)
Chr.	Chromosome 13 (mouse)
End	72,782,317 bp
RNA expression pattern
	Top expressed in
	skin of arm; ; lower lobe of lung; ; lactiferous duct; ; parotid gland; ; skin of thigh; ; Pons; ; renal medulla; ; bronchial epithelial cell; ; nipple; ; buccal mucosa cell;
	Top expressed in
	pretectal area; ; otic placode; ; lip; ; otic vesicle; ; saccule; ; lacrimal gland; ; epidermis; ; zone of skin; ; skin of abdomen; ; skin of back;
	More reference expression data
	n/a
Gene ontology
Molecular function	DNA binding; DNA-binding transcription repressor activity, RNA polymerase II-specific; sequence-specific DNA binding; DNA-binding transcription factor activity, RNA polymerase II-specific;
Cellular component	nucleus;
Biological process	specification of loop of Henle identity; metanephros development; regulation of transcription, DNA-templated; proximal/distal pattern formation involved in metanephric nephron development; negative regulation of transcription by RNA polymerase II;
	Sources:Amigo / QuickGO
Orthologs
	153572
	16372
	ENSG00000170561
	ENSMUSG00000001504
	Q9BZI1
	P81066
	NM_001134222; NM_033267
	NM_010574
	NP_001127694; NP_150366
	NP_034704
	Wikidata
View/Edit Human	View/Edit Mouse

Iroquois-class homeodomain protein IRX-2, also known as Iroquois homeobox protein 2, is a protein that in humans is encoded by the IRX2 gene.