ISCA1

ISCA1
Identifiers
Aliases	ISCA1, HBLD2, ISA1, hIscA, iron-sulfur cluster assembly 1, MMDS5
External IDs	OMIM: 611006; MGI: 1916296; HomoloGene: 87862; GeneCards: ISCA1; OMA:ISCA1 - orthologs
Gene location (Human)
Chr.	Chromosome 9 (human)
End	86,283,102 bp
Gene location (Mouse)
Chr.	Chromosome 13 (mouse)
End	59,917,624 bp
RNA expression pattern
	Top expressed in
	endothelial cell; ; biceps brachii; ; Skeletal muscle tissue of biceps brachii; ; right ventricle; ; trabecular bone; ; kidney tubule; ; Epithelium of choroid plexus; ; Pons; ; myocardium; ; Brodmann area 23;
	Top expressed in
	bone marrow; ; brown adipose tissue; ; tibialis anterior muscle; ; soleus muscle; ; quadriceps femoris muscle; ; masseter muscle; ; extraocular muscle; ; myocardium of ventricle; ; muscle of thigh; ; cardiac muscles;
	More reference expression data
	n/a
Gene ontology
Molecular function	iron-sulfur cluster binding; ferrous iron binding; structural molecule activity; metal ion binding; 2 iron, 2 sulfur cluster binding;
Cellular component	mitochondrion; mitochondrial matrix;
Biological process	iron-sulfur cluster assembly; protein maturation by iron-sulfur cluster transfer; small molecule metabolic process;
	Sources:Amigo / QuickGO
Orthologs
	81689
	69046
	ENSG00000135070
	ENSMUSG00000044792
	Q9BUE6
	Q9D924
	NM_030940
	NM_026921
	NP_112202
	NP_081197
	Wikidata
View/Edit Human	View/Edit Mouse

Iron-sulfur cluster assembly 1 homolog, mitochondrial is an evolutionarily highly conserved protein for the biogenesis of iron-sulfur cluster across species. In humans it is encoded by the ISCA1 gene.