Integrin beta 8

ITGB8
Identifiers
Aliases	ITGB8, integrin subunit beta 8
External IDs	OMIM: 604160; MGI: 1338035; HomoloGene: 18567; GeneCards: ITGB8; OMA:ITGB8 - orthologs
Gene location (Human)
Chr.	Chromosome 7 (human)
End	20,415,754 bp
Gene location (Mouse)
Chr.	Chromosome 12 (mouse)
End	119,202,537 bp
RNA expression pattern
	Top expressed in
	retinal pigment epithelium; ; external globus pallidus; ; ventricular zone; ; synovial joint; ; spinal ganglia; ; bronchial epithelial cell; ; corpus epididymis; ; mucosa of paranasal sinus; ; trigeminal ganglion; ; caput epididymis;
	Top expressed in
	retinal pigment epithelium; ; Epithelium of choroid plexus; ; suprachiasmatic nucleus; ; deep cerebellar nuclei; ; olfactory tubercle; ; sciatic nerve; ; substantia nigra; ; otolith organ; ; utricle; ; medial vestibular nucleus;
	More reference expression data
	; ;
	More reference expression data
Gene ontology
Molecular function	signaling receptor binding; extracellular matrix protein binding; integrin binding; signaling receptor activity;
Cellular component	integrin alphav-beta8 complex; integral component of membrane; cell surface; integrin complex; plasma membrane; extracellular exosome; membrane; focal adhesion;
Biological process	integrin-mediated signaling pathway; cartilage development; placenta blood vessel development; cell adhesion; ganglioside metabolic process; positive regulation of gene expression; extracellular matrix organization; cell-matrix adhesion; negative regulation of gene expression; vasculogenesis; cell migration; cell adhesion mediated by integrin; positive regulation of angiogenesis; regulation of transforming growth factor beta activation;
	Sources:Amigo / QuickGO
Orthologs
	3696
	320910
	ENSG00000105855
	ENSMUSG00000025321
	P26012
	Q0VBD0
	NM_002214
	NM_177290
	NP_002205
	NP_796264
	Wikidata
View/Edit Human	View/Edit Mouse

Integrin beta-8 is a protein that in humans is encoded by the ITGB8 gene.