ITIH4

ITIH4
Identifiers
Aliases	ITIH4, GP120, H4P, IHRP, ITI-HC4, ITIHL1, PK-120, PK120, inter-alpha-trypsin inhibitor heavy chain family member 4, inter-alpha-trypsin inhibitor heavy chain 4
External IDs	OMIM: 600564; MGI: 109536; HomoloGene: 1670; GeneCards: ITIH4; OMA:ITIH4 - orthologs
Gene location (Human)
Chr.	Chromosome 3 (human)
End	52,830,688 bp
Gene location (Mouse)
Chr.	Chromosome 14 (mouse)
End	30,624,310 bp
RNA expression pattern
	Top expressed in
	right lobe of liver; ; right coronary artery; ; popliteal artery; ; tibial arteries; ; left coronary artery; ; body of pancreas; ; muscle of thigh; ; sperm; ; right adrenal cortex; ; gastrocnemius muscle;
	Top expressed in
	left lobe of liver; ; ascending aorta; ; aortic valve; ; gallbladder; ; tunica media of zone of aorta; ; right lung lobe; ; carotid body; ; sexually immature organism; ; fetal liver hematopoietic progenitor cell; ; embryo;
	More reference expression data
	n/a
Gene ontology
Molecular function	peptidase inhibitor activity; endopeptidase inhibitor activity; protein binding; serine-type endopeptidase inhibitor activity;
Cellular component	cytoplasm; plasma membrane; blood microparticle; extracellular exosome; platelet dense granule lumen; extracellular region; collagen-containing extracellular matrix;
Biological process	response to cytokine; negative regulation of peptidase activity; acute-phase response; hyaluronan metabolic process; platelet degranulation; negative regulation of endopeptidase activity;
	Sources:Amigo / QuickGO
Orthologs
	3700
	16427
	ENSG00000055955
	ENSMUSG00000021922
	Q14624
	A6X935
	NM_002218; NM_001166449
	NM_001159299; NM_001289632; NM_001289633; NM_018746
	NP_001159921; NP_002209
	NP_001152771; NP_001276561; NP_001276562; NP_061216
	Wikidata
View/Edit Human	View/Edit Mouse

Inter-alpha-trypsin inhibitor heavy chain H4 is a protein that in humans is encoded by the ITIH4 gene.