ITPKB

ITPKB
Identifiers
Aliases	ITPKB, IP3-3KB, IP3K, IP3K-B, IP3KB, PIG37, inositol-trisphosphate 3-kinase B
External IDs	OMIM: 147522; MGI: 109235; HomoloGene: 1672; GeneCards: ITPKB; OMA:ITPKB - orthologs
Gene location (Human)
Chr.	Chromosome 1 (human)
End	226,739,323 bp
Gene location (Mouse)
Chr.	Chromosome 1 (mouse)
End	180,252,367 bp
RNA expression pattern
	Top expressed in
	external globus pallidus; ; pars reticulata; ; dorsal motor nucleus of vagus nerve; ; internal globus pallidus; ; inferior olivary nucleus; ; pars compacta; ; subthalamic nucleus; ; ventral tegmental area; ; superior vestibular nucleus; ; middle frontal gyrus;
	Top expressed in
	choroid plexus of fourth ventricle; ; lactiferous gland; ; sciatic nerve; ; islet of Langerhans; ; right lung; ; internal carotid artery; ; blood; ; thymus; ; left lung; ; right lung lobe;
	More reference expression data
	More reference expression data
Gene ontology
Molecular function	transferase activity; nucleotide binding; calmodulin binding; kinase activity; protein binding; ATP binding; inositol-1,4,5-trisphosphate 3-kinase activity;
Cellular component	cytosol; membrane; nucleus;
Biological process	regulation of protein phosphorylation; cellular response to calcium ion; negative regulation of neutrophil apoptotic process; phosphorylation; common myeloid progenitor cell proliferation; myeloid cell homeostasis; positive regulation of Ras protein signal transduction; inositol phosphate metabolic process; inositol trisphosphate metabolic process; MAPK cascade; cell surface receptor signaling pathway; T cell differentiation; positive thymic T cell selection; negative regulation of myeloid cell differentiation; positive regulation of alpha-beta T cell differentiation; thymic T cell selection; signal transduction; inositol phosphate biosynthetic process;
	Sources:Amigo / QuickGO
Orthologs
	3707
	320404
	ENSG00000143772
	ENSMUSG00000038855
	P27987
	B2RXC2
	NM_002221; NM_001388404
	NM_001081175
	NP_002212
	NP_001074644
	Wikidata
View/Edit Human	View/Edit Mouse

Inositol-trisphosphate 3-kinase B is an enzyme that in humans is encoded by the ITPKB gene.