Imipenem/cilastatin/relebactam

< Imipenem < cilastatin

Imipenem/cilastatin/relebactam
Combination of
Imipenemβ-Lactam antibiotic
CilastatinDehydropeptidase inhibitor
Relebactamβ-Lactamase inhibitor
Clinical data
Trade namesRecarbrio
Other namesMK-7655A
AHFS/Drugs.comMonograph
MedlinePlusa619046
License data
Routes of
administration		Intravenous
ATC code
Legal status
Legal status
  • US: ℞-only
  • EU: Rx-only
  • In general: ℞ (Prescription only)
Identifiers
CAS Number
KEGG

Imipenem/cilastatin/relebactam, sold under the brand name Recarbrio(Merck), is a fixed-dose combination medication used as an antibiotic. In 2019, it was approved for use in the United States for the treatment of complicated urinary tract and complicated intra-abdominal infections. It is administered via intravenous injection.

The most common adverse reactions include nausea, diarrhea, headache, fever and increased liver enzymes.

The most common adverse reactions observed in people treated for hospital-acquired bacterial pneumonia and ventilator-associated bacterial pneumonia (HABP/VABP) include increased aspartate/alanine aminotransferases (increased liver enzymes), anemia, diarrhea, hypokalemia (low potassium), and hyponatremia (low sodium).

This article is issued from Wikipedia. The text is licensed under Creative Commons - Attribution - Sharealike. Additional terms may apply for the media files.