Immune-mediated necrotizing myopathy

Immune-mediated necrotizing myopathy (IMNM) is a subgroup of the idiopathic inflammatory myopathies. There are three major subtypes based on autoantibodies, of which statin-associated autoimmune myopathy has been increasing in recent years. It is characterized by myopathological findings of multiple necrotic and regenerating fibers with little infiltration of inflammatory cells.