Interleukin-7 receptor
| Interleukin-7 receptor-α | |||||||
|---|---|---|---|---|---|---|---|
| Identifiers | |||||||
| Symbol | IL7R | ||||||
| Alt. symbols | CD127 | ||||||
| NCBI gene | 3575 | ||||||
| HGNC | 6024 | ||||||
| OMIM | 146661 | ||||||
| RefSeq | NM_002185 | ||||||
| UniProt | P16871 | ||||||
| Other data | |||||||
| Locus | Chr. 5 p13 | ||||||
| |||||||
| interleukin 2 receptor, gamma | |||||||
|---|---|---|---|---|---|---|---|
| Identifiers | |||||||
| Symbol | IL2RG | ||||||
| Alt. symbols | SCIDX1, IMD4, CD132 | ||||||
| NCBI gene | 3561 | ||||||
| HGNC | 6010 | ||||||
| OMIM | 308380 | ||||||
| RefSeq | NM_000206 | ||||||
| UniProt | P31785 | ||||||
| Other data | |||||||
| Locus | Chr. X q13 | ||||||
| |||||||
The interleukin-7 receptor is a protein found on the surface of cells. It is made up of two different smaller protein chains - i.e. it is a heterodimer, and consists of two subunits, interleukin-7 receptor-α (CD127) and common-γ chain receptor (CD132). The common-γ chain receptors is shared with various cytokines, including interleukin-2, -4, -9, and -15. Interleukin-7 receptor is expressed on various cell types, including naive and memory T cells and many others.