Interstate 10 in California

Interstate 10 (I-10) is a transcontinental Interstate Highway in the United States, stretching from Santa Monica, California, to Jacksonville, Florida. The segment of I-10 in California, also known as the Pearl Harbor Memorial Highway, runs east from Santa Monica through Los Angeles, San Bernardino, and Palm Springs before crossing into the state of Arizona. In the Greater Los Angeles area, it is known as the Santa Monica and San Bernardino freeways, linked by a short concurrency on I-5 (Golden State Freeway) at the East Los Angeles Interchange. I-10 also has parts designated as the Rosa Parks and Sonny Bono Memorial freeways. Some parts were also formerly designated as the Christopher Columbus Transcontinental Highway. However, the California State Legislature removed this designation following the passage of a bill on August 31, 2022. I-10 is also known colloquially as "the 10" to Southern California residents (See also California English § Freeways).

The entirety of Interstate 10 in California is defined in the California Streets and Highways Code as Route 10.