Interstate 55
| I-55 highlighted in red | |
| Route information | |
| Length | 964.25 mi (1,551.81 km) | 
| Existed | 1957–present | 
| NHS | Entire route | 
| Major junctions | |
| South end | I-10 in LaPlace, LA | 
| 
 | |
| North end | US 41 in Chicago, IL | 
| Location | |
| Country | United States | 
| States | Louisiana, Mississippi, Tennessee, Arkansas, Missouri, Illinois | 
| Highway system | |
Interstate 55 (I-55) is a major Interstate Highway in the central United States. As with most primary Interstates that end in a five, it is a major cross-country, north–south route, connecting the Gulf of Mexico to the Great Lakes. The highway travels from LaPlace, Louisiana, at I-10 to Chicago, Illinois, at Lake Shore Drive (US 41), near McCormick Place. The major cities that I-55 connects to are (from south to north) Jackson, Mississippi; Memphis, Tennessee; and St. Louis, Missouri.
The section of I-55 between Chicago and St. Louis was built as an alternate route for U.S. Route 66 (US 66). The Interstate crosses the Mississippi River twice: once at Memphis and again at St. Louis.