Isolation Drills is the 12th studio album by American indie rock band Guided by Voices. It was their second and final LP released under TVT Records and their second to feature a major rock producer in Rob Schnapf. The album was also their first to chart on the Billboard 200, peaking at number 168. The album notably features instrumental contributions from Elliott Smith and David Sulzer. Previous longtime band member Tobin Sprout also returned as a guest and contributed with playing piano. While Jim MacPherson plays drums on the album, his replacement Jon McCann is featured in the cover photos, as MacPherson had left the band immediately after the recording to focus on his home life.