Isse Mohamoud
| Ciise Dhuux | |
|---|---|
| Regions with significant populations | |
| Nugal, Lower Juba, Bari mudug sool | |
| Languages | |
| Af-Somali, Arabic, | |
| Religion | |
| Islam | |
| Related ethnic groups | |
| Osman Mahmoud, Omar Mahmoud, Majeerteen | 
Isse Mohamoud or Eisse Mahmoud (Somali: Ciise Maxamuud; Arabic: عِيْسَىُ مَحَمُوْدً) is a prominent sub-clan within the Majertein clan in Somalia, comprising a significant population in four regional states primarily located in Puntland.