JAG2

JAG2
Identifiers
Aliases	JAG2, HJ2, SER2, jagged 2, jagged canonical Notch ligand 2, LGMDR27
External IDs	OMIM: 602570; MGI: 1098270; HomoloGene: 1677; GeneCards: JAG2; OMA:JAG2 - orthologs
Gene location (Human)
Chr.	Chromosome 14 (human)
End	105,168,824 bp
Gene location (Mouse)
Chr.	Chromosome 12 (mouse)
End	112,893,396 bp
RNA expression pattern
	Top expressed in
	nipple; ; apex of heart; ; pituitary gland; ; skin of abdomen; ; anterior pituitary; ; skin of leg; ; skin of thigh; ; endothelial cell; ; olfactory zone of nasal mucosa; ; right frontal lobe;
	Top expressed in
	lip; ; primary oocyte; ; molar; ; secondary oocyte; ; esophagus; ; superior frontal gyrus; ; corneal stroma; ; hair follicle; ; muscle of thigh; ; external carotid artery;
	More reference expression data
	; ;
	More reference expression data
Gene ontology
Molecular function	calcium ion binding; Notch binding; protein binding; growth factor activity;
Cellular component	integral component of membrane; membrane; plasma membrane; integral component of plasma membrane;
Biological process	Notch signaling pathway; skeletal system development; respiratory system process; epithelial cell apoptotic process involved in palatal shelf morphogenesis; in utero embryonic development; multicellular organism development; odontogenesis of dentin-containing tooth; cell communication; auditory receptor cell fate commitment; T cell differentiation; regulation of cell adhesion; spermatogenesis; morphogenesis of embryonic epithelium; gamma-delta T cell differentiation; thymic T cell selection; positive regulation of Notch signaling pathway; cell differentiation; regulation of cell population proliferation; regulation of signaling receptor activity; negative regulation of Notch signaling pathway;
	Sources:Amigo / QuickGO
Orthologs
	3714
	16450
	ENSG00000184916
	ENSMUSG00000002799
	Q9Y219
	Q9QYE5
	NM_002226; NM_145159
	NM_010588
	NP_002217; NP_660142
	NP_034718
	Wikidata
View/Edit Human	View/Edit Mouse

Jagged-2 is a protein that in humans is encoded by the JAG2 gene.