JAM2

JAM2
Identifiers
Aliases	JAM2, C21orf43, CD322, JAM-B, JAMB, PRO245, VE-JAM, VEJAM, junctional adhesion molecule 2, IBGC8
External IDs	OMIM: 606870; MGI: 1933820; HomoloGene: 10929; GeneCards: JAM2; OMA:JAM2 - orthologs
Gene location (Human)
Chr.	Chromosome 21 (human)
End	25,717,562 bp
Gene location (Mouse)
Chr.	Chromosome 16 (mouse)
End	84,622,816 bp
RNA expression pattern
	Top expressed in
	ventricular zone; ; tendon of biceps brachii; ; vena cava; ; internal globus pallidus; ; ganglionic eminence; ; pericardium; ; gastric mucosa; ; body of uterus; ; epithelium of colon; ; tibial nerve;
	Top expressed in
	interventricular septum; ; myocardium of ventricle; ; cumulus cell; ; right ventricle; ; cardiac muscles; ; neural layer of retina; ; deep cerebellar nuclei; ; iris; ; epithelium of lens; ; substantia nigra;
	More reference expression data
	More reference expression data
Gene ontology
Molecular function	protein binding; protein heterodimerization activity;
Cellular component	integral component of membrane; cell junction; plasma membrane; integral component of plasma membrane; membrane; bicellular tight junction;
Biological process	negative regulation of cell adhesion; extracellular matrix organization; leukocyte migration; cell-cell adhesion;
	Sources:Amigo / QuickGO
Orthologs
	58494
	67374
	ENSG00000154721
	ENSMUSG00000053062
	P57087
	Q9JI59
	NM_001270407; NM_001270408; NM_021219
	NM_023844
	NP_001257336; NP_001257337; NP_067042
	NP_076333
	Wikidata
View/Edit Human	View/Edit Mouse

Junctional adhesion molecule B is a protein that in humans is encoded by the JAM2 gene. JAM2 has also been designated as CD322 (cluster of differentiation 322).