JAZF1

JAZF1
Identifiers
Aliases	JAZF1, TIP27, ZNF802, JAZF zinc finger 1
External IDs	OMIM: 606246; MGI: 2141450; HomoloGene: 18291; GeneCards: JAZF1; OMA:JAZF1 - orthologs
Gene location (Human)
Chr.	Chromosome 7 (human)
End	28,180,795 bp
Gene location (Mouse)
Chr.	Chromosome 6 (mouse)
End	53,045,616 bp
RNA expression pattern
	Top expressed in
	trabecular bone; ; tail of epididymis; ; right adrenal cortex; ; left adrenal cortex; ; urethra; ; endometrium; ; oocyte; ; decidua; ; secondary oocyte; ; smooth muscle tissue;
	Top expressed in
	zygote; ; secondary oocyte; ; epithelium of lens; ; primary oocyte; ; interventricular septum; ; Region I of hippocampus proper; ; dentate gyrus of hippocampal formation granule cell; ; spermatocyte; ; uterus; ; arcuate nucleus;
	More reference expression data
	n/a
Gene ontology
Molecular function	nucleic acid binding; metal ion binding; transcription corepressor activity; DNA-binding transcription factor activity, RNA polymerase II-specific; protein binding;
Cellular component	transcription repressor complex; fibrillar center; nucleus; cytosol;
Biological process	lipid metabolism; transcription, DNA-templated; negative regulation of transcription by RNA polymerase II; regulation of transcription, DNA-templated;
	Sources:Amigo / QuickGO
Orthologs
	221895
	231986
	ENSG00000153814
	ENSMUSG00000063568
	Q86VZ6
	Q80ZQ5
	NM_175061
	NM_001168277; NM_173406
	NP_778231
	NP_001161749; NP_775582
	Wikidata
View/Edit Human	View/Edit Mouse

Juxtaposed with another zinc finger protein 1 (JAZF1) also known as TAK1-interacting protein 27 (TIP27) or zinc finger protein 802 (ZNF802) is a protein that in humans is encoded by the JAZF1 gene. Variants are associated with an increased risk of prostate cancer, an increased risk of type 2 diabetes, and an increased height.