JUNB

JUNB
Identifiers
Aliases	JUNB, AP-1, JunB proto-oncogene, AP-1 transcription factor subunit
External IDs	OMIM: 165161; MGI: 96647; HomoloGene: 7390; GeneCards: JUNB; OMA:JUNB - orthologs
Gene location (Human)
Chr.	Chromosome 19 (human)
End	12,793,315 bp
Gene location (Mouse)
Chr.	Chromosome 8 (mouse)
End	85,705,347 bp
RNA expression pattern
	Top expressed in
	gastric mucosa; ; left uterine tube; ; granulocyte; ; monocyte; ; tibial arteries; ; vena cava; ; saphenous vein; ; left ovary; ; nipple; ; trachea;
	Top expressed in
	granulocyte; ; lip; ; superior surface of tongue; ; spermatid; ; spermatocyte; ; corneal stroma; ; visual cortex; ; esophagus; ; transitional epithelium of urinary bladder; ; primary visual cortex;
	More reference expression data
	More reference expression data
Gene ontology
Molecular function	DNA binding; RNA polymerase II transcription regulatory region sequence-specific DNA binding; transcription corepressor activity; DNA-binding transcription factor activity; transcription coactivator activity; DNA-binding transcription activator activity, RNA polymerase II-specific; transcription factor binding; RNA polymerase II cis-regulatory region sequence-specific DNA binding; protein binding; DNA-binding transcription factor activity, RNA polymerase II-specific;
Cellular component	nucleoplasm; chromatin; nucleus; transcription factor AP-1 complex; transcription regulator complex;
Biological process	cellular response to calcium ion; regulation of transcription, DNA-templated; regulation of transcription by RNA polymerase II; regulation of cell death; osteoclast differentiation; labyrinthine layer blood vessel development; in utero embryonic development; negative regulation of transcription by RNA polymerase II; transcription by RNA polymerase II; regulation of cell cycle; vasculogenesis; embryonic process involved in female pregnancy; response to lipopolysaccharide; decidualization; regulation of cell population proliferation; trophectodermal cell differentiation; osteoblast differentiation; positive regulation of cell differentiation; response to radiation; osteoblast proliferation; cellular process or phenomenon; response to cAMP; response to mechanical stimulus; transcription, DNA-templated; cellular response to hormone stimulus; response to cytokine; positive regulation of transcription by RNA polymerase II; cytokine-mediated signaling pathway; response to organic substance;
	Sources:Amigo / QuickGO
Orthologs
	3726
	16477
	ENSG00000171223
	ENSMUSG00000052837
	P17275
	P09450
	NM_002229
	NM_008416
	NP_002220
	NP_032442
	Wikidata
View/Edit Human	View/Edit Mouse

Transcription factor jun-B is a protein that, in humans, is encoded by the JUNB gene. Transcription factor jun-B is a transcription factor involved in regulating gene activity following the primary growth factor response. It binds to the DNA sequence 5'-TGA[CG]TCA-3'.