Jackson–Weiss syndrome

Jackson–Weiss syndrome
Other namesCraniosynostosis, midfacial hypoplasia, and foot abnormalities
Jackson–Weiss syndrome is inherited in an autosomal dominant pattern
SymptomsHypertelorism
CausesMutations in the FGFR2 gene
Diagnostic methodGenetic testing
TreatmentSurgery

Jackson–Weiss syndrome (JWS) is a genetic disorder characterized by foot abnormalities and the premature fusion of certain bones of the skull (craniosynostosis), which prevents further growth of the skull and affects the shape of the head and face. This genetic disorder can also sometimes cause intellectual disability and crossed eyes. It was characterized in 1976.