Jacob Duché Sr.

Colonel Jacob Duché (1708–1788) was a mayor of Philadelphia in the colonial province of Pennsylvania.

Duché was born in Philadelphia, the son of Anthony Duché (c. 1682-1762), a potter from a Huguenot family who had emigrated to England. Anthony had come with his wife to America in the same ship as William Penn in about 1700. Jacob was appointed a colonel of the militia. He served as mayor of Philadelphia from 1761 to 1762. He became a member of the American Philosophical Society through his election in 1768.

He was for many years a vestryman of Christ Church; when the congregation grew too large to be accommodated there, he headed the committee that oversaw the erection of its daughter church, St. Peter's.