James Coyne
James Coyne could refer to:
- James Henry Coyne (1849–1942), Canadian lawyer and historian
 - James Bowes Coyne, Canadian lawyer and jurist, son of Henry
 - James Elliott Coyne (1910–2012), Canadian Governor of the Bank of Canada, son of Bowes
 - James K. Coyne III (born 1946), U.S. Representative from Pennsylvania
 - James C. Coyne (1947-2024), American psychologist