James Hopkins
James Hopkins may refer to:
- James Hopkins (footballer, born 1873) (1873–?), English association football player for Manchester United
 - James Hopkins (footballer, born 1901) (1901–1943), Northern Irish association football player for Arsenal and Brighton
 - James C. Hopkins (architect) (1873–1938), Massachusetts architect, partner in Kilham & Hopkins
 - James C. Hopkins, Jr. (architect) (c. 1914–1998), his son, also architectural firm partner
 - James C. Hopkins (lawyer) (1819–1877), legislator, lawyer, and judge of New York and Wisconsin
 - James Frank Hopkins (1845–1913), Confederate Army volunteer and founder of the Sigma Nu fraternity at the VMI
 - James G. Hopkins (1801–1860), New York politician
 - James Herron Hopkins (1832–1904), American politician
 - James Scott-Hopkins (1921–1995), British Conservative Party politician
 - Jim Hopkins (born 1946), New Zealand TV personality
 - Jimmy Hopkins, fictional character in the video game, Bully