Dutasteride/tamsulosin
< Dutasteride
| Combination of | |
|---|---|
| Dutasteride | 5α-Reductase inhibitor |
| Tamsulosin | Alpha-1 blocker |
| Clinical data | |
| Trade names | Jalyn |
| AHFS/Drugs.com | Professional Drug Facts |
| License data | |
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| Routes of administration | By mouth |
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Dutasteride/tamsulosin, sold under the brand name Jalyn among others, is a medication produced by GlaxoSmithKline for the treatment of adult male symptomatic benign prostatic hyperplasia (BPH). It is a combination of two previously existing medications: dutasteride, brand name Avodart, and tamsulosin, brand name Flomax. It contains 0.5 mg of dutasteride and 0.4 mg of tamsulosin hydrochloride.
Jalyn was the result of the CombAT (Combination of Avodart and Tamsulosin) trial of 2008. It was approved by the U.S. Food and Drug Administration (FDA) on June 14, 2010. In June 2011, the FDA approved a label change to warn of "Increased Risk of High-grade Prostate Cancer" from Jalyn.