KCND2

KCND2
Identifiers
Aliases	KCND2, KV4.2, RK5, potassium voltage-gated channel subfamily D member 2
External IDs	OMIM: 605410; MGI: 102663; HomoloGene: 40828; GeneCards: KCND2; OMA:KCND2 - orthologs
Gene location (Human)
Chr.	Chromosome 7 (human)
End	120,750,337 bp
Gene location (Mouse)
Chr.	Chromosome 6 (mouse)
End	21,729,804 bp
RNA expression pattern
	Top expressed in
	cerebellar vermis; ; paraflocculus of cerebellum; ; lateral nuclear group of thalamus; ; Pons; ; stromal cell of endometrium; ; right hemisphere of cerebellum; ; Brodmann area 23; ; prefrontal cortex; ; primary visual cortex; ; ganglionic eminence;
	Top expressed in
	lobe of cerebellum; ; habenula; ; cerebellar vermis; ; toe; ; medial geniculate nucleus; ; medial dorsal nucleus; ; third toe; ; olfactory tubercle; ; nucleus accumbens; ; lateral geniculate nucleus;
	More reference expression data
	n/a
Gene ontology
Molecular function	potassium channel activity; metal ion binding; voltage-gated ion channel activity; ion channel activity; protein binding; A-type (transient outward) potassium channel activity; voltage-gated potassium channel activity; voltage-gated ion channel activity involved in regulation of postsynaptic membrane potential;
Cellular component	integral component of membrane; perikaryon; postsynaptic membrane; cell projection; membrane; plasma membrane raft; intrinsic component of plasma membrane; voltage-gated potassium channel complex; plasma membrane; dendritic spine; synapse; integral component of plasma membrane; neuronal cell body membrane; cell junction; soma; dendrite; glutamatergic synapse; GABA-ergic synapse; integral component of postsynaptic membrane; integral component of postsynaptic specialization membrane; postsynaptic density;
Biological process	chemical synaptic transmission; regulation of ion transmembrane transport; ion transport; potassium ion transport; transmembrane transport; potassium ion transmembrane transport; action potential; sensory perception of pain; protein homooligomerization; cellular response to hypoxia; neuronal action potential; locomotor rhythm; regulation of postsynaptic membrane potential; cardiac conduction;
	Sources:Amigo / QuickGO
Orthologs
	3751
	16508
	ENSG00000184408
	ENSMUSG00000060882
	Q9NZV8
	Q9Z0V2
	NM_012281
	NM_019697
	NP_036413
	NP_062671
	Wikidata
View/Edit Human	View/Edit Mouse

Potassium voltage-gated channel subfamily D member 2 is a protein that in humans is encoded by the KCND2 gene. It contributes to the cardiac transient outward potassium current (I_to1), the main contributing current to the repolarizing phase 1 of the cardiac action potential.