KCNE3

KCNE3
Identifiers
Aliases	KCNE3, HOKPP, HYPP, MiRP2, potassium voltage-gated channel subfamily E regulatory subunit 3, BRGDA6
External IDs	OMIM: 604433; MGI: 1891124; HomoloGene: 3994; GeneCards: KCNE3; OMA:KCNE3 - orthologs
Gene location (Human)
Chr.	Chromosome 11 (human)
End	74,467,729 bp
Gene location (Mouse)
Chr.	Chromosome 7 (mouse)
End	99,834,076 bp
RNA expression pattern
	Top expressed in
	nasal epithelium; ; monocyte; ; mucosa of ileum; ; duodenum; ; bronchial epithelial cell; ; mucosa of sigmoid colon; ; pancreatic ductal cell; ; pylorus; ; rectum; ; blood;
	Top expressed in
	spermatid; ; left colon; ; crypt of lieberkuhn of small intestine; ; spermatocyte; ; seminiferous tubule; ; duodenum; ; Paneth cell; ; migratory enteric neural crest cell; ; jejunum; ; ileum;
	More reference expression data
	More reference expression data
Gene ontology
Molecular function	potassium channel activity; transmembrane transporter binding; voltage-gated ion channel activity; potassium channel regulator activity; protein binding; voltage-gated potassium channel activity; delayed rectifier potassium channel activity; voltage-gated potassium channel activity involved in ventricular cardiac muscle cell action potential repolarization;
Cellular component	cytoplasm; integral component of membrane; vesicle; perikaryon; cell projection; membrane; voltage-gated potassium channel complex; plasma membrane; neuronal cell body membrane; dendrite; membrane raft;
Biological process	regulation of potassium ion transport; positive regulation of voltage-gated calcium channel activity; regulation of ion transmembrane transport; ion transport; potassium ion transport; potassium ion transmembrane transport; negative regulation of delayed rectifier potassium channel activity; regulation of heart rate by cardiac conduction; negative regulation of potassium ion export across plasma membrane; negative regulation of voltage-gated potassium channel activity; negative regulation of membrane repolarization during ventricular cardiac muscle cell action potential; regulation of ventricular cardiac muscle cell membrane repolarization; ventricular cardiac muscle cell action potential; membrane repolarization during action potential; membrane repolarization during ventricular cardiac muscle cell action potential; potassium ion export across plasma membrane;
	Sources:Amigo / QuickGO
Orthologs
	10008
	57442
	ENSG00000175538
	ENSMUSG00000035165
	Q9Y6H6
	Q9WTW2
	NM_005472
NM_001190869; NM_001190870; NM_001190871; NM_001190950; NM_020574;
	NM_001360466; NM_001360467
	NP_005463
NP_001177798; NP_001177799; NP_001177800; NP_001177879; NP_065599;
	NP_001347395; NP_001347396
	Wikidata
View/Edit Human	View/Edit Mouse

Potassium voltage-gated channel, Isk-related family, member 3 (KCNE3), also known as MinK-related peptide 2 (MiRP2) is a protein that in humans is encoded by the KCNE3 gene.