KCNJ12

KCNJ12
Identifiers
Aliases	KCNJ12, IRK-2, IRK2, KCNJN1, Kir2.2, Kir2.2v, hIRK, hIRK1, hkir2.2x, kcnj12x, potassium voltage-gated channel subfamily J member 12, potassium inwardly rectifying channel subfamily J member 12
External IDs	OMIM: 602323; MGI: 108495; HomoloGene: 7793; GeneCards: KCNJ12; OMA:KCNJ12 - orthologs
Gene location (Human)
Chr.	Chromosome 17 (human)
End	21,419,870 bp
Gene location (Mouse)
Chr.	Chromosome 11 (mouse)
End	60,961,957 bp
RNA expression pattern
	Top expressed in
	Skeletal muscle tissue of rectus abdominis; ; cerebellar vermis; ; muscle of thigh; ; cerebellar hemisphere; ; right hemisphere of cerebellum; ; gastrocnemius muscle; ; quadriceps femoris muscle; ; vastus lateralis muscle; ; tibialis anterior muscle; ; Skeletal muscle tissue of biceps brachii;
	Top expressed in
	muscle of thigh; ; cerebellar cortex; ; lumbar spinal ganglion; ; sternocleidomastoid muscle; ; lens; ; triceps brachii muscle; ; skeletal muscle tissue; ; knee joint; ; temporal muscle; ; quadriceps femoris muscle;
	More reference expression data
	; ;
	More reference expression data
Gene ontology
Molecular function	inward rectifier potassium channel activity; voltage-gated ion channel activity; G-protein activated inward rectifier potassium channel activity; protein binding;
Cellular component	integral component of membrane; intrinsic component of membrane; plasma membrane; integral component of plasma membrane; membrane;
Biological process	potassium ion transport; regulation of ion transmembrane transport; muscle contraction; regulation of heart contraction; protein homotetramerization; ion transport; potassium ion import across plasma membrane; cardiac conduction;
	Sources:Amigo / QuickGO
Orthologs
	3768
	16515
	ENSG00000184185
	ENSMUSG00000042529
	Q14500
	P52187
	NM_021012
	NM_001267593; NM_010603
	NP_066292
	NP_001254522; NP_034733
	Wikidata
View/Edit Human	View/Edit Mouse

ATP-sensitive inward rectifier potassium channel 12 is a lipid-gated ion channel that in humans is encoded by the KCNJ12 gene.