KCNJ14

KCNJ14
Identifiers
Aliases	KCNJ14, IRK4, KIR2.4, potassium voltage-gated channel subfamily J member 14, potassium inwardly rectifying channel subfamily J member 14
External IDs	OMIM: 603953; MGI: 2384820; HomoloGene: 27086; GeneCards: KCNJ14; OMA:KCNJ14 - orthologs
Gene location (Human)
Chr.	Chromosome 19 (human)
End	48,466,980 bp
Gene location (Mouse)
Chr.	Chromosome 7 (mouse)
End	45,474,206 bp
RNA expression pattern
	Top expressed in
	putamen; ; stromal cell of endometrium; ; gastrocnemius muscle; ; skin of leg; ; primary visual cortex; ; ventricular zone; ; skin of abdomen; ; muscle of thigh; ; caudate nucleus; ; skeletal muscle tissue;
	Top expressed in
	layer of retina; ; neural layer of retina; ; anterior horn of spinal cord; ; eyelid; ; olfactory cortex; ; spinal ganglia; ; lower eyelid; ; Amygdala; ; upper eyelid; ; trigeminal ganglion;
	More reference expression data
	More reference expression data
Gene ontology
Molecular function	voltage-gated ion channel activity; inward rectifier potassium channel activity;
Cellular component	integral component of membrane; voltage-gated potassium channel complex; soma; plasma membrane; dendrite; membrane;
Biological process	potassium ion transport; regulation of ion transmembrane transport; ion transport; potassium ion import across plasma membrane; cardiac conduction;
	Sources:Amigo / QuickGO
Orthologs
	3770
	211480
	ENSG00000182324
	ENSMUSG00000058743
	Q9UNX9
	Q8JZN3
	NM_170720; NM_013348
	NM_145963
	NP_037480
	NP_666075
	Wikidata
View/Edit Human	View/Edit Mouse

Potassium inwardly-rectifying channel, subfamily J, member 14 (KCNJ14), also known as K_ir2.4, is a human gene.

Potassium channels are present in most mammalian cells, where they participate in a wide range of physiologic responses. The protein encoded by this gene is an integral membrane protein and inward-rectifier type potassium channel, and probably has a role in controlling the excitability of motor neurons. Two transcript variants encoding the same protein have been found for this gene.