KCNJ5

KCNJ5
Identifiers
Aliases	KCNJ5, CIR, GIRK4, KATP1, KIR3.4, LQT13, potassium voltage-gated channel subfamily J member 5, potassium inwardly rectifying channel subfamily J member 5
External IDs	OMIM: 600734; MGI: 104755; HomoloGene: 20248; GeneCards: KCNJ5; OMA:KCNJ5 - orthologs
Gene location (Human)
Chr.	Chromosome 11 (human)
End	128,921,163 bp
Gene location (Mouse)
Chr.	Chromosome 9 (mouse)
End	32,255,646 bp
RNA expression pattern
	Top expressed in
	buccal mucosa cell; ; endothelial cell; ; adrenal cortex; ; right adrenal gland; ; left adrenal gland; ; left adrenal cortex; ; right adrenal cortex; ; tendon of biceps brachii; ; right ventricle; ; myocardium;
	Top expressed in
	atrium; ; atrioventricular valve; ; aortic valve; ; olfactory epithelium; ; endocardial cushion; ; right lobe of liver; ; myocardium of ventricle; ; supraoptic nucleus; ; right ventricle; ; embryo;
	More reference expression data
	n/a
Gene ontology
Molecular function	G-protein activated inward rectifier potassium channel activity; protein binding; inward rectifier potassium channel activity; voltage-gated ion channel activity; voltage-gated potassium channel activity involved in atrial cardiac muscle cell action potential repolarization; voltage-gated potassium channel activity involved in ventricular cardiac muscle cell action potential repolarization;
Cellular component	integral component of membrane; T-tubule; plasma membrane; membrane; external side of plasma membrane; voltage-gated potassium channel complex;
Biological process	potassium ion transport; regulation of ion transmembrane transport; ion transport; regulation of heart rate by cardiac conduction; membrane repolarization during atrial cardiac muscle cell action potential; membrane repolarization during ventricular cardiac muscle cell action potential; ventricular cardiac muscle cell membrane repolarization; potassium ion import across plasma membrane;
	Sources:Amigo / QuickGO
Orthologs
	3762
	16521
	ENSG00000120457
	ENSMUSG00000032034
	P48544
	P48545
	NM_000890; NM_001354169
	NM_010605
	NP_000881; NP_001341098
	NP_034735
	Wikidata
View/Edit Human	View/Edit Mouse

G protein-activated inward rectifier potassium channel 4 (GIRK-4) is a protein that in humans is encoded by the KCNJ5 gene and is a type of G protein-gated ion channel.