KDM4B

KDM4B
Available structures
PDB	Ortholog search: PDBe RCSB
List of PDB id codes
	4LXL, 4UC4
Identifiers
Aliases	KDM4B, JMJD2B, TDRD14B, lysine demethylase 4B, MRD65
External IDs	OMIM: 609765; MGI: 2442355; HomoloGene: 27773; GeneCards: KDM4B; OMA:KDM4B - orthologs
Gene location (Human)
Chr.	Chromosome 19 (human)
End	5,153,598 bp
Gene location (Mouse)
Chr.	Chromosome 17 (mouse)
End	56,709,870 bp
RNA expression pattern
	Top expressed in
	dorsal motor nucleus of vagus nerve; ; corpus epididymis; ; blood; ; caput epididymis; ; inferior olivary nucleus; ; sural nerve; ; parotid gland; ; tendon of biceps brachii; ; nipple; ; Skeletal muscle tissue of biceps brachii;
	Top expressed in
	Rostral migratory stream; ; lip; ; neural layer of retina; ; superior frontal gyrus; ; otic vesicle; ; primary visual cortex; ; external carotid artery; ; dentate gyrus of hippocampal formation granule cell; ; granulocyte; ; muscle of thigh;
	More reference expression data
	; ; ; ;
	More reference expression data
Gene ontology
Molecular function	oxidoreductase activity; dioxygenase activity; metal ion binding; histone demethylase activity; histone H3-methyl-lysine-36 demethylase activity; histone H3-methyl-lysine-9 demethylase activity; DNA-binding transcription repressor activity, RNA polymerase II-specific; chromatin binding; methylated histone binding;
Cellular component	nucleoplasm; nucleus; histone methyltransferase complex;
Biological process	regulation of transcription, DNA-templated; transcription, DNA-templated; histone H3-K36 demethylation; histone H3-K9 demethylation; chromatin organization; negative regulation of transcription by RNA polymerase II; chromatin remodeling;
	Sources:Amigo / QuickGO
Orthologs
	23030
	193796
	ENSG00000127663
	ENSMUSG00000024201
	O94953
	Q91VY5
	NM_015015; NM_001370093; NM_001370094
	NM_172132; NM_001357909
	NP_055830; NP_001357022; NP_001357023
	NP_742144; NP_001344838
	Wikidata
View/Edit Human	View/Edit Mouse

Lysine-specific demethylase 4B is an enzyme that in humans is encoded by the KDM4B gene. KDM4B belongs to the alpha-ketoglutarate-dependent hydroxylase superfamily.