KDM4C

KDM4C
Available structures
PDB	Ortholog search: PDBe RCSB
List of PDB id codes
	2XDP, 2XML, 4XDO, 4XDP, 5FJK, 5FJH
Identifiers
Aliases	KDM4C, GASC1, JHDM3C, JMJD2C, TDRD14C, bA146B14.1, lysine demethylase 4C
External IDs	OMIM: 605469; MGI: 1924054; HomoloGene: 41004; GeneCards: KDM4C; OMA:KDM4C - orthologs
Gene location (Human)
Chr.	Chromosome 9 (human)
End	7,175,648 bp
Gene location (Mouse)
Chr.	Chromosome 4 (mouse)
End	74,324,097 bp
RNA expression pattern
	Top expressed in
	right hemisphere of cerebellum; ; epithelium of colon; ; bone marrow cells; ; tonsil; ; Achilles tendon; ; sural nerve; ; corpus callosum; ; body of pancreas; ; monocyte; ; granulocyte;
	Top expressed in
	saccule; ; neural layer of retina; ; otic vesicle; ; otic placode; ; lacrimal gland; ; retinal pigment epithelium; ; granulocyte; ; interventricular septum; ; pineal gland; ; superior cervical ganglion;
	More reference expression data
	; ;
	More reference expression data
Gene ontology
Molecular function	oxidoreductase activity; histone H3-methyl-lysine-9 demethylase activity; dioxygenase activity; metal ion binding; chromatin binding; enzyme binding; histone demethylase activity; androgen receptor binding; zinc ion binding; histone H3-methyl-lysine-36 demethylase activity; DNA-binding transcription repressor activity, RNA polymerase II-specific; methylated histone binding;
Cellular component	nucleus; nucleoplasm; pericentric heterochromatin; histone methyltransferase complex;
Biological process	regulation of transcription by RNA polymerase II; regulation of transcription, DNA-templated; transcription, DNA-templated; positive regulation of cell population proliferation; blastocyst formation; regulation of gene expression; positive regulation of gene expression; histone H3-K9 demethylation; positive regulation of neuron differentiation; negative regulation of histone H3-K9 trimethylation; regulation of stem cell population maintenance; regulation of stem cell differentiation; histone H3-K36 demethylation; chromatin organization; negative regulation of transcription by RNA polymerase II; chromatin remodeling; stem cell population maintenance;
	Sources:Amigo / QuickGO
Orthologs
	23081
	76804
	ENSG00000107077
	ENSMUSG00000028397
	Q9H3R0
	Q8VCD7
NM_001146694; NM_001146695; NM_001146696; NM_001304339; NM_001304340;
	NM_001304341; NM_015061; NM_001353997; NM_001353998; NM_001353999; NM_001354000; NM_001354001
	NM_001172095; NM_144787; NM_001356561
NP_001140167; NP_001140168; NP_001291268; NP_001291269; NP_001291270;
	NP_055876; NP_001340926; NP_001340927; NP_001340928; NP_001340929; NP_001340930
	NP_001165566; NP_659036; NP_001343490
	Wikidata
View/Edit Human	View/Edit Mouse

Lysine-specific demethylase 4C is an enzyme that in humans is encoded by the KDM4C gene.