KDM6B

KDM6B
Available structures
PDB	Ortholog search: PDBe RCSB
List of PDB id codes
	2XUE, 2XXZ, 4ASK, 5FP3
Identifiers
Aliases	KDM6B, JMJD3, lysine demethylase 6B, NEDCFSA
External IDs	OMIM: 611577; MGI: 2448492; HomoloGene: 18945; GeneCards: KDM6B; OMA:KDM6B - orthologs
Gene location (Human)
Chr.	Chromosome 17 (human)
End	7,854,796 bp
Gene location (Mouse)
Chr.	Chromosome 11 (mouse)
End	69,413,675 bp
RNA expression pattern
	Top expressed in
	blood; ; sural nerve; ; granulocyte; ; epithelium of colon; ; mucosa of ileum; ; left ovary; ; right ovary; ; ganglionic eminence; ; anterior pituitary; ; left uterine tube;
	Top expressed in
	internal carotid artery; ; Rostral migratory stream; ; external carotid artery; ; otolith organ; ; utricle; ; hand; ; secondary oocyte; ; vestibular membrane of cochlear duct; ; primitive streak; ; hair follicle;
	More reference expression data
	n/a
Gene ontology
Molecular function	sequence-specific DNA binding; beta-catenin binding; chromatin binding; dioxygenase activity; metal ion binding; protein binding; oxidoreductase activity; histone demethylase activity; histone H3-tri/di-methyl-lysine-27 demethylase activity; RNA polymerase II cis-regulatory region sequence-specific DNA binding; chromatin DNA binding;
Cellular component	nucleoplasm; nucleus; MLL3/4 complex;
Biological process	response to fungicide; histone demethylation; cell fate commitment; inflammatory response to antigenic stimulus; cardiac muscle cell differentiation; response to activity; mesodermal cell differentiation; regulation of gene expression; endothelial cell differentiation; inflammatory response; hippocampus development; positive regulation of transcription by RNA polymerase II; cellular response to hydrogen peroxide; histone H3-K27 demethylation; chromatin remodeling; chromatin organization; positive regulation of cold-induced thermogenesis;
	Sources:Amigo / QuickGO
Orthologs
	23135
	216850
	ENSG00000132510
	ENSMUSG00000018476
	O15054
	Q5NCY0
	NM_001080424; NM_001348716
	NM_001017426
	NP_001073893; NP_001335645
	NP_001017426
	Wikidata
View/Edit Human	View/Edit Mouse

Lysine demethylase 6B is a protein that in humans is encoded by the KDM6B (JMJD3) gene.