KIF2A

KIF2A
Available structures
PDB	Ortholog search: PDBe RCSB
List of PDB id codes
	2GRY
Identifiers
Aliases	KIF2A, CDCBM3, HK2, KIF2, kinesin heavy chain member 2A, kinesin family member 2A
External IDs	OMIM: 602591; MGI: 108390; HomoloGene: 3320; GeneCards: KIF2A; OMA:KIF2A - orthologs
Gene location (Human)
Chr.	Chromosome 5 (human)
End	62,391,025 bp
Gene location (Mouse)
Chr.	Chromosome 13 (mouse)
End	107,158,634 bp
RNA expression pattern
	Top expressed in
	corpus callosum; ; ganglionic eminence; ; monocyte; ; sperm; ; ventricular zone; ; external globus pallidus; ; sural nerve; ; subthalamic nucleus; ; pars compacta; ; superior vestibular nucleus;
	Top expressed in
	barrel cortex; ; blood; ; genital tubercle; ; habenula; ; tail of embryo; ; zygote; ; secondary oocyte; ; olfactory bulb; ; facial motor nucleus; ; spermatid;
	More reference expression data
	; ; ; ;
	More reference expression data
Gene ontology
Molecular function	microtubule motor activity; nucleotide binding; microtubule binding; ATPase activity; protein binding; cytoskeletal motor activity; ATP binding;
Cellular component	cytoplasm; cytosol; centrosome; spindle pole; membrane; kinesin complex; spindle; microtubule organizing center; sperm principal piece; spindle microtubule; nucleolus; microtubule; cytoskeleton; nucleus; nuclear body; centriole; centriolar subdistal appendage;
Biological process	cell differentiation; antigen processing and presentation of exogenous peptide antigen via MHC class II; mitotic spindle organization; nervous system development; cell division; multicellular organism development; microtubule-based movement; mitotic spindle assembly; cell cycle; retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum; sister chromatid cohesion; microtubule cytoskeleton organization; microtubule depolymerization; regulation of cell migration;
	Sources:Amigo / QuickGO
Orthologs
	3796
	16563
	ENSG00000068796
	ENSMUSG00000021693
	O00139
	P28740
	NM_004520; NM_001098511; NM_001243952; NM_001243953
NM_001145779; NM_008442; NM_001374727; NM_001378936; NM_001378937;
	NM_001378938; NM_001378939; NM_001378940
	NP_001091981; NP_001230881; NP_001230882; NP_004511
NP_001139251; NP_032468; NP_001361656; NP_001365865; NP_001365866;
	NP_001365867; NP_001365868; NP_001365869
	Wikidata
View/Edit Human	View/Edit Mouse

Kinesin-like protein KIF2A is a protein that in humans is encoded by the KIF2A gene. In mice, KIF2A is essential for proper neurogenesis and deficiency of KIF2A in mature neurons results in the loss of those neurons.

Kinesins, such as KIF2, are microtubule-associated motor proteins. For background information on kinesins, see MIM 148760.[supplied by OMIM]