KIN (gene)

KIN
Available structures
PDBOrtholog search: PDBe RCSB
Identifiers
AliasesKIN, BTCD, KIN17, Rts2, Kin17 DNA and RNA binding protein
External IDsOMIM: 601720; MGI: 96676; HomoloGene: 8196; GeneCards: KIN; OMA:KIN - orthologs
Orthologs
SpeciesHumanMouse
Entrez

22944

16588

Ensembl

ENSG00000151657

ENSMUSG00000037262

UniProt

O60870

Q8K339

RefSeq (mRNA)

NM_012311

NM_025280

RefSeq (protein)

NP_036443

NP_079556

Location (UCSC)Chr 10: 7.75 – 7.79 MbChr 2: 10.09 – 10.1 Mb
PubMed search
Wikidata
View/Edit HumanView/Edit Mouse

DNA/RNA-binding protein KIN17 is a protein that in humans is encoded by the KIN gene.

The protein encoded by this gene is a nuclear protein that forms intranuclear foci during proliferation and is redistributed in the nucleoplasm during the cell cycle. Short-wave ultraviolet light provokes the relocalization of the protein, suggesting its participation in the cellular response to DNA damage. Originally selected based on protein-binding with RecA antibodies, the mouse protein presents a limited similarity with a functional domain of the bacterial RecA protein, a characteristic shared by this human ortholog.