KIRREL2

KIRREL2
Identifiers
Aliases	KIRREL2, FILTRIN, NEPH3, NLG1, kin of IRRE like 2 (Drosophila), kirre like nephrin family adhesion molecule 2
External IDs	OMIM: 607762; MGI: 2442334; HomoloGene: 35249; GeneCards: KIRREL2; OMA:KIRREL2 - orthologs
Gene location (Human)
Chr.	Chromosome 19 (human)
End	35,867,136 bp
Gene location (Mouse)
Chr.	Chromosome 7 (mouse)
End	30,157,115 bp
RNA expression pattern
	Top expressed in
	body of pancreas; ; islet of Langerhans; ; ventricular zone; ; ganglionic eminence; ; retinal pigment epithelium; ; prefrontal cortex; ; external globus pallidus; ; lymph node; ; Brodmann area 9; ; cingulate gyrus;
	Top expressed in
	primary visual cortex; ; superior frontal gyrus; ; dentate gyrus of hippocampal formation granule cell; ; white matter of cerebellum; ; respiratory epithelium; ; striatum of neuraxis; ; islet of Langerhans; ; spinal cord; ; nasal epithelium; ; rhombic lip;
	More reference expression data
	More reference expression data
Gene ontology
Molecular function	protein binding; identical protein binding;
Cellular component	integral component of membrane; slit diaphragm; membrane; plasma membrane; cell-cell junction;
Biological process	negative regulation of protein phosphorylation; cell adhesion; cell-cell adhesion;
	Sources:Amigo / QuickGO
Orthologs
	84063
	243911
	ENSG00000126259
	ENSMUSG00000036915
	Q6UWL6
	Q7TSU7
	NM_032123; NM_199179; NM_199180; NM_001329530; NM_001363667
	NM_172898
	NP_001316459; NP_115499; NP_954648; NP_954649; NP_001350596
	NP_766486
	Wikidata
View/Edit Human	View/Edit Mouse

Kin of IRRE-like protein 2, also known as NEPH3, is a protein that in humans is encoded by the KIRREL2 gene. It is primarily expressed in β cells of the pancreatic islets.

KIRREL2 is a member of the NEPH protein family, which includes NEPH1 (KIRREL) and NEPH2 (KIRREL3).