KLC2

KLC2
Available structures
PDB	Ortholog search: PDBe RCSB
List of PDB id codes
	3CEQ, 3EDT
Identifiers
Aliases	KLC2, kinesin light chain 2
External IDs	OMIM: 611729; MGI: 107953; HomoloGene: 22468; GeneCards: KLC2; OMA:KLC2 - orthologs
Gene location (Human)
Chr.	Chromosome 11 (human)
End	66,267,860 bp
Gene location (Mouse)
Chr.	Chromosome 19 (mouse)
End	5,168,588 bp
RNA expression pattern
	Top expressed in
	right hemisphere of cerebellum; ; right frontal lobe; ; prefrontal cortex; ; Brodmann area 9; ; anterior cingulate cortex; ; right testis; ; endothelial cell; ; left testis; ; anterior pituitary; ; primary visual cortex;
	Top expressed in
	superior frontal gyrus; ; primary visual cortex; ; cerebellar cortex; ; dentate gyrus of hippocampal formation granule cell; ; neural layer of retina; ; pontine nuclei; ; superior colliculus; ; inferior colliculi; ; muscle of thigh; ; Medulla Oblongata;
	More reference expression data
	More reference expression data
Gene ontology
Molecular function	microtubule motor activity; protein binding; kinesin binding; cadherin binding;
Cellular component	cytoplasm; cytosol; microtubule; cytoskeleton; membrane; kinesin I complex; kinesin complex; nucleoplasm; mitochondrion; plasma membrane; protein-containing complex;
Biological process	microtubule-based movement; antigen processing and presentation of exogenous peptide antigen via MHC class II; retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum;
	Sources:Amigo / QuickGO
Orthologs
	64837
	16594
	ENSG00000174996
	ENSMUSG00000024862
	Q9H0B6
	O88448
	NM_001134774; NM_001134775; NM_001134776; NM_022822; NM_001318734
	NM_008451; NM_001369360; NM_001369361; NM_001369362
	NP_001128246; NP_001128247; NP_001128248; NP_001305663; NP_073733
	n/a
	Wikidata
View/Edit Human	View/Edit Mouse

Kinesin light chain 2 is a protein that in humans is encoded by the KLC2 gene. This gene is responsible for SPOAN syndrome, a type of hereditary spastic paraplegia.