KLF15

KLF15
Available structures
PDB	Ortholog search: PDBe RCSB
List of PDB id codes
	2ENT
Identifiers
Aliases	KLF15, KKLF, Kruppel-like factor 15, Kruppel like factor 15
External IDs	OMIM: 606465; MGI: 1929988; HomoloGene: 8553; GeneCards: KLF15; OMA:KLF15 - orthologs
Gene location (Human)
Chr.	Chromosome 3 (human)
End	126,357,408 bp
Gene location (Mouse)
Chr.	Chromosome 6 (mouse)
End	90,452,220 bp
RNA expression pattern
	Top expressed in
	parotid gland; ; cardia; ; lower lobe of lung; ; sural nerve; ; renal medulla; ; gastric mucosa; ; right lobe of liver; ; inferior ganglion of vagus nerve; ; ventral tegmental area; ; external globus pallidus;
	Top expressed in
	left lobe of liver; ; lacrimal gland; ; interventricular septum; ; vestibular membrane of cochlear duct; ; right kidney; ; proximal tubule; ; muscle of thigh; ; masseter muscle; ; parotid gland; ; retinal pigment epithelium;
	More reference expression data
	n/a
Gene ontology
Molecular function	DNA-binding transcription factor activity; DNA binding; DNA-binding transcription activator activity, RNA polymerase II-specific; protein binding; metal ion binding; nucleic acid binding; DNA-binding transcription factor activity, RNA polymerase II-specific; RNA polymerase II transcription regulatory region sequence-specific DNA binding; RNA polymerase II cis-regulatory region sequence-specific DNA binding;
Cellular component	nucleus;
Biological process	regulation of gene expression; glomerular visceral epithelial cell differentiation; positive regulation of transcription, DNA-templated; negative regulation of peptidyl-lysine acetylation; glial cell differentiation; cardiac muscle hypertrophy in response to stress; regulation of transcription, DNA-templated; positive regulation of transcription by RNA polymerase II; transcription, DNA-templated; transcription by RNA polymerase II; positive regulation of glucose import; regulation of transcription by RNA polymerase II; cellular glucose homeostasis; response to insulin; cellular response to peptide;
	Sources:Amigo / QuickGO
Orthologs
	28999
	66277
	ENSG00000163884
	ENSMUSG00000030087
	Q9UIH9
	Q9EPW2
	NM_014079
	NM_023184; NM_001355668
	NP_054798
	NP_075673; NP_001342597
	Wikidata
View/Edit Human	View/Edit Mouse

Krüppel-like factor 15 is a protein that in humans is encoded by the KLF15 gene in the Krüppel-like factor family. Its former designation KKLF stands for kidney-enriched Krüppel-like factor.