KLF6

KLF6
Identifiers
Aliases	KLF6, BCD1, CBA1, COPEB, CPBP, GBF, PAC1, ST12, ZF9, Kruppel-like factor 6, Kruppel like factor 6
External IDs	OMIM: 602053; MGI: 1346318; HomoloGene: 996; GeneCards: KLF6; OMA:KLF6 - orthologs
Gene location (Human)
Chr.	Chromosome 10 (human)
End	3,785,281 bp
Gene location (Mouse)
Chr.	Chromosome 13 (mouse)
End	5,920,393 bp
RNA expression pattern
	Top expressed in
	nipple; ; lower lobe of lung; ; skin of thigh; ; saphenous vein; ; vena cava; ; pericardium; ; gastric mucosa; ; skin of hip; ; monocyte; ; synovial joint;
	Top expressed in
	granulocyte; ; stroma of bone marrow; ; aortic valve; ; ascending aorta; ; sciatic nerve; ; endothelial cell of lymphatic vessel; ; left colon; ; tunica media of zone of aorta; ; right lung lobe; ; blood;
	More reference expression data
	; ; ; ;
	More reference expression data
Gene ontology
Molecular function	DNA binding; protein binding; metal ion binding; nucleic acid binding; RNA polymerase II cis-regulatory region sequence-specific DNA binding; DNA-binding transcription activator activity, RNA polymerase II-specific; DNA-binding transcription factor activity, RNA polymerase II-specific; double-stranded DNA binding;
Cellular component	fibrillar center; nucleus; nucleolus; cytosol; intracellular membrane-bounded organelle;
Biological process	positive regulation of transcription, DNA-templated; B cell differentiation; regulation of transcription, DNA-templated; transcription, DNA-templated; positive regulation of transcription by RNA polymerase II; transcription by RNA polymerase II; regulation of transcription by RNA polymerase II; cytokine-mediated signaling pathway;
	Sources:Amigo / QuickGO
Orthologs
	1316
	23849
	ENSG00000067082
	ENSMUSG00000000078
	Q99612
	O08584; Q8BPQ2
	NM_001008490; NM_001160124; NM_001160125; NM_001300
	NM_011803
	NP_001153596; NP_001153597; NP_001291
	NP_035933
	Wikidata
View/Edit Human	View/Edit Mouse

Krueppel-like factor 6 is a protein that in humans is encoded by the KLF6 gene.

It is a tumor suppressor gene.