KLF8

KLF8
Identifiers
Aliases	KLF8, BKLF3, ZNF741, Kruppel-like factor 8, Kruppel like factor 8
External IDs	OMIM: 300286; MGI: 2442430; HomoloGene: 68549; GeneCards: KLF8; OMA:KLF8 - orthologs
Gene location (Human)
Chr.	X chromosome (human)
End	56,291,531 bp
Gene location (Mouse)
Chr.	X chromosome (mouse)
End	152,179,128 bp
RNA expression pattern
	Top expressed in
	skin of abdomen; ; oral cavity; ; skin of leg; ; vagina; ; skin of thigh; ; popliteal artery; ; tibial arteries; ; skin of hip; ; parietal pleura; ; gingival epithelium;
	Top expressed in
	placenta; ; morula; ; ganglionic eminence; ; epiblast; ; blastocyst; ; embryo; ; granulocyte; ; yolk sac; ; Mesencephalon; ; ventricular zone;
	More reference expression data
	More reference expression data
Gene ontology
Molecular function	DNA binding; metal ion binding; nucleic acid binding; RNA polymerase II cis-regulatory region sequence-specific DNA binding; DNA-binding transcription repressor activity, RNA polymerase II-specific; DNA-binding transcription factor activity, RNA polymerase II-specific;
Cellular component	nucleus; nucleoplasm; cytosol; aggresome;
Biological process	regulation of transcription, DNA-templated; transcription, DNA-templated; negative regulation of transcription by RNA polymerase II; regulation of transcription by RNA polymerase II;
	Sources:Amigo / QuickGO
Orthologs
	11279
	245671
	ENSG00000102349
	ENSMUSG00000041649
	O95600
	Q8BLM0
NM_001159296; NM_007250; NM_001324099; NM_001324100; NM_001324102;
	NM_001324104; NM_001324105
	NM_173780; NM_001357183
NP_001152768; NP_001311028; NP_001311029; NP_001311031; NP_001311033;
	NP_001311034; NP_009181
	NP_776141; NP_001344112
	Wikidata
View/Edit Human	View/Edit Mouse

Krueppel-like factor 8 is a protein that in humans is encoded by the KLF8 gene. KLF8 belongs to the family of KLF protein. KLF8 is activated by KLF1 along with KLF3 while KLF3 represses KLF8.