Kelch-like protein 1

KLHL1
Identifiers
Aliases	KLHL1, MRP2, kelch like family member 1
External IDs	OMIM: 605332; MGI: 2136335; HomoloGene: 56903; GeneCards: KLHL1; OMA:KLHL1 - orthologs
Gene location (Human)
Chr.	Chromosome 13 (human)
End	70,108,493 bp
Gene location (Mouse)
Chr.	Chromosome 14 (mouse)
End	96,756,538 bp
RNA expression pattern
	Top expressed in
	pars reticulata; ; pars compacta; ; testicle; ; superior vestibular nucleus; ; ventral tegmental area; ; Pons; ; Hypothalamus; ; islet of Langerhans; ; ganglionic eminence; ; prefrontal cortex;
	Top expressed in
	ventral tegmental area; ; substantia nigra; ; lumbar subsegment of spinal cord; ; lateral hypothalamus; ; habenula; ; ventromedial nucleus; ; mammillary body; ; supraoptic nucleus; ; central gray substance of midbrain; ; medial vestibular nucleus;
	More reference expression data
	n/a
Gene ontology
Molecular function	ubiquitin-protein transferase activity; actin binding;
Cellular component	Cul3-RING ubiquitin ligase complex; cytoskeleton; dendrite; soma; cytoplasm;
Biological process	cerebellar Purkinje cell layer development; actin cytoskeleton organization; locomotory behavior; adult walking behavior; dendrite development; protein ubiquitination;
	Sources:Amigo / QuickGO
Orthologs
	57626
	93688
	ENSG00000150361
	ENSMUSG00000022076
	Q9NR64
	Q9JI74
	NM_020866; NM_001286725
	NM_053105
	NP_001273654; NP_065917
	NP_444335
	Wikidata
View/Edit Human	View/Edit Mouse

Kelch-like protein 1 is a protein that in humans is encoded by the KLHL1 gene.