Kelch-like protein 12

KLHL12
Available structures
PDB	Ortholog search: PDBe RCSB
List of PDB id codes
	2VPJ
Identifiers
Aliases	KLHL12, C3IP1, DKIR, hDKIR, kelch like family member 12
External IDs	OMIM: 614522; MGI: 2385619; HomoloGene: 23317; GeneCards: KLHL12; OMA:KLHL12 - orthologs
Gene location (Human)
Chr.	Chromosome 1 (human)
End	202,928,636 bp
Gene location (Mouse)
Chr.	Chromosome 1 (mouse)
End	134,418,756 bp
RNA expression pattern
	Top expressed in
	oocyte; ; secondary oocyte; ; mucosa of ileum; ; myocardium of left ventricle; ; gonad; ; cardiac muscle tissue of right atrium; ; middle temporal gyrus; ; sperm; ; ventricular zone; ; right testis;
	Top expressed in
	otolith organ; ; utricle; ; hand; ; substantia nigra; ; neural layer of retina; ; Paneth cell; ; granulocyte; ; trigeminal ganglion; ; epithelium of lens; ; tail of embryo;
	More reference expression data
	More reference expression data
Gene ontology
Molecular function	ubiquitin-protein transferase activity; protein binding; identical protein binding;
Cellular component	cytosol; COPII-coated ER to Golgi transport vesicle; Cul3-RING ubiquitin ligase complex; intracellular membrane-bounded organelle; cytoplasmic vesicle; microtubule organizing center; Golgi membrane; COPII vesicle coat;
Biological process	COPII vesicle coating; Wnt signaling pathway; protein monoubiquitination; negative regulation of canonical Wnt signaling pathway; vesicle-mediated transport; protein ubiquitination; endoplasmic reticulum to Golgi vesicle-mediated transport; neural crest formation; neural crest cell development;
	Sources:Amigo / QuickGO
Orthologs
	59349
	240756
	ENSG00000117153
	ENSMUSG00000026455
	Q53G59
	Q8BZM0
	NM_001303051; NM_001303109; NM_021633
	NM_153128; NM_001311136
	NP_001289980; NP_001290038; NP_067646
	NP_001298065; NP_694768
	Wikidata
View/Edit Human	View/Edit Mouse

Kelch-like protein 12 is a protein that in humans is encoded by the KLHL12 gene.