Kelch-like protein 2

KLHL2
Available structures
PDB	Ortholog search: PDBe RCSB
List of PDB id codes
	2XN4, 4CHB
Identifiers
Aliases	KLHL2, ABP-KELCH, MAV, MAYVEN, kelch like family member 2
External IDs	OMIM: 605774; MGI: 1924363; HomoloGene: 21416; GeneCards: KLHL2; OMA:KLHL2 - orthologs
Gene location (Human)
Chr.	Chromosome 4 (human)
End	165,323,156 bp
Gene location (Mouse)
Chr.	Chromosome 8 (mouse)
End	65,302,669 bp
RNA expression pattern
	Top expressed in
	Brodmann area 23; ; Region I of hippocampus proper; ; postcentral gyrus; ; optic nerve; ; external globus pallidus; ; superior frontal gyrus; ; middle temporal gyrus; ; dorsal motor nucleus of vagus nerve; ; Brodmann area 46; ; orbitofrontal cortex;
	Top expressed in
	olfactory tubercle; ; nucleus accumbens; ; dentate gyrus; ; subdivision of hippocampus; ; globus pallidus; ; Region I of hippocampus proper; ; primary motor cortex; ; hippocampus proper; ; piriform cortex; ; cumulus cell;
	More reference expression data
	n/a
Gene ontology
Molecular function	ubiquitin-protein transferase activity; protein binding; actin binding; identical protein binding;
Cellular component	ruffle; cell projection; actin cytoskeleton; lamellipodium; cytoskeleton; cytoplasm; Cul3-RING ubiquitin ligase complex; cytosol;
Biological process	protein ubiquitination; post-translational protein modification;
	Sources:Amigo / QuickGO
Orthologs
	11275
	77113
	ENSG00000109466
	ENSMUSG00000031605
	O95198
	Q8JZP3
	NM_001161521; NM_001161522; NM_007246; NM_001331023; NM_001331024
	NM_178633
	NP_001154993; NP_001154994; NP_001317952; NP_001317953; NP_009177
	NP_848748
	Wikidata
View/Edit Human	View/Edit Mouse

Kelch-like family member 2 is a protein that in humans is encoded by the KLHL2 gene.