KLK10

KLK10
Available structures
PDBOrtholog search: PDBe RCSB
Identifiers
AliasesKLK10, NES1, PRSSL1, kallikrein related peptidase 10
External IDsOMIM: 602673; MGI: 1916790; HomoloGene: 26428; GeneCards: KLK10; OMA:KLK10 - orthologs
Orthologs
SpeciesHumanMouse
Entrez

5655

69540

Ensembl

ENSG00000129451

ENSMUSG00000030693

UniProt

O43240

Q99M20

RefSeq (mRNA)

NM_001077500
NM_002776
NM_145888

NM_133712

RefSeq (protein)

NP_001070968
NP_002767
NP_665895

NP_598473

Location (UCSC)Chr 19: 51.01 – 51.02 MbChr 7: 43.43 – 43.43 Mb
PubMed search
Wikidata
View/Edit HumanView/Edit Mouse

Kallikrein-10 is a protein that in humans is encoded by the KLK10 gene.

Kallikreins are a subgroup of serine proteases having diverse physiological functions. Growing evidence suggests that many kallikreins are implicated in carcinogenesis and some have potential as novel cancer and other disease biomarkers. This gene is one of the fifteen kallikrein subfamily members located in a cluster on chromosome 19. Its encoded protein is secreted and may play a role in suppression of tumorigenesis in breast and prostate cancers. Alternate splicing of this gene results in multiple transcript variants encoding the same protein.