KLK11

KLK11
Identifiers
AliasesKLK11, PRSS20, TLSP, kallikrein related peptidase 11
External IDsOMIM: 604434; MGI: 1929977; HomoloGene: 27048; GeneCards: KLK11; OMA:KLK11 - orthologs
Orthologs
SpeciesHumanMouse
Entrez

11012

56538

Ensembl

ENSG00000167757

ENSMUSG00000067616

UniProt

Q9UBX7

Q9QYN3

RefSeq (mRNA)

NM_001136032
NM_001167605
NM_006853
NM_144947

NM_001177373
NM_019974

RefSeq (protein)

NP_001129504
NP_001161077
NP_006844
NP_659196

NP_001170844
NP_064358

Location (UCSC)Chr 19: 51.02 – 51.03 MbChr 7: 43.42 – 43.43 Mb
PubMed search
Wikidata
View/Edit HumanView/Edit Mouse

Kallikrein-11 is a protein that in humans is encoded by the KLK11 gene.

Kallikreins are a subgroup of serine proteases having diverse physiological functions. Growing evidence suggests that many kallikreins are implicated in carcinogenesis and some have potential as novel cancer and other disease biomarkers. This gene is one of the fifteen kallikrein subfamily members located in a cluster on chromosome 19. Alternate splicing of this gene results in two transcript variants encoding two different isoforms which are differentially expressed.