KLK12

KLK12
Identifiers
AliasesKLK12, KLK-L5, KLKL5, kallikrein related peptidase 12
External IDsOMIM: 605539; MGI: 1916761; HomoloGene: 44690; GeneCards: KLK12; OMA:KLK12 - orthologs
Orthologs
SpeciesHumanMouse
Entrez

43849

69511

Ensembl

ENSG00000186474

ENSMUSG00000044430

UniProt

Q9UKR0

B2RVZ0

RefSeq (mRNA)

NM_027097

RefSeq (protein)

NP_081373

Location (UCSC)Chr 19: 51.03 – 51.04 MbChr 7: 43.42 – 43.42 Mb
PubMed search
Wikidata
View/Edit HumanView/Edit Mouse

Kallikrein-12 is a protein that in humans is encoded by the KLK12 gene.

Kallikreins are a subgroup of serine proteases having diverse physiological functions. Growing evidence suggests that many kallikreins are implicated in carcinogenesis and some have potential as novel cancer and other disease biomarkers. This gene is one of the fifteen kallikrein subfamily members located in a cluster on chromosome 19. Alternate splicing of this gene results in three transcript variants encoding different isoforms.