KMT2E

KMT2E
Available structures
PDB	Ortholog search: PDBe RCSB
List of PDB id codes
	2LV9, 4L58
Identifiers
Aliases	KMT2E, HDCMC04P, MLL5, NKp44L, lysine methyltransferase 2E, ODLURO, lysine methyltransferase 2E (inactive), SETD5B
External IDs	OMIM: 608444; MGI: 1924825; HomoloGene: 18822; GeneCards: KMT2E; OMA:KMT2E - orthologs
Gene location (Human)
Chr.	Chromosome 7 (human)
End	105,115,019 bp
Gene location (Mouse)
Chr.	Chromosome 5 (mouse)
End	23,709,233 bp
RNA expression pattern
	Top expressed in
	tendon of biceps brachii; ; mucosa of paranasal sinus; ; Achilles tendon; ; sperm; ; internal globus pallidus; ; pylorus; ; buccal mucosa cell; ; visceral pleura; ; corpus callosum; ; epithelium of colon;
	Top expressed in
	Rostral migratory stream; ; genital tubercle; ; cumulus cell; ; parotid gland; ; conjunctival fornix; ; tail of embryo; ; human fetus; ; ascending aorta; ; pineal gland; ; blood;
	More reference expression data
	n/a
Gene ontology
Molecular function	metal ion binding; protein binding; histone-lysine N-methyltransferase activity; enzyme binding; methylated histone binding;
Cellular component	cytoplasm; nuclear speck; membrane; plasma membrane; chromatin; nucleus; nucleoplasm; chromosome; microtubule organizing center; cytoskeleton; protein-containing complex;
Biological process	neutrophil activation; regulation of transcription, DNA-templated; transcription, DNA-templated; DNA methylation; erythrocyte differentiation; cell cycle; neutrophil mediated immunity; histone lysine methylation; regulation of megakaryocyte differentiation; positive regulation of transcription, DNA-templated; positive regulation of G1/S transition of mitotic cell cycle; positive regulation of histone H3-K4 trimethylation; chromatin organization;
	Sources:Amigo / QuickGO
Orthologs
	55904
	69188
	ENSG00000005483
	ENSMUSG00000029004
	Q8IZD2
	Q3UG20
	NM_018682; NM_032187; NM_182931
	NM_026984
	NP_061152; NP_891847
	NP_081260
	Wikidata
View/Edit Human	View/Edit Mouse

Lysine methyltransferase 2E is a protein that in humans is encoded by the KMT2E gene.