Keratin 12

KRT12
Identifiers
Aliases	KRT12, K12, keratin 12, MECD1
External IDs	OMIM: 601687; MGI: 96687; HomoloGene: 188; GeneCards: KRT12; OMA:KRT12 - orthologs
Gene location (Human)
Chr.	Chromosome 17 (human)
End	40,867,223 bp
Gene location (Mouse)
Chr.	Chromosome 11 (mouse)
End	99,313,085 bp
RNA expression pattern
	Top expressed in
	gonad; ; testicle; ; mucosa of transverse colon; ; eye; ; duodenum; ; skin of abdomen; ; rectum; ; skin of leg; ; vagina; ; ectocervix;
	Top expressed in
	corneal stroma; ; ciliary body; ; conjunctival fornix; ; epithelium of lens; ; retinal pigment epithelium; ; primary oocyte; ; olfactory tubercle; ; piriform cortex; ; secondary oocyte; ; iris;
	More reference expression data
	n/a
Gene ontology
Molecular function	structural molecule activity;
Cellular component	intermediate filament; extracellular exosome; cytosol;
Biological process	visual perception; keratinization; cornification;
	Sources:Amigo / QuickGO
Orthologs
	3859
	268482
	ENSG00000187242
	ENSMUSG00000020912
	Q99456
	Q64291
	NM_000223
	NM_010661
	NP_000214
	NP_034791
	Wikidata
View/Edit Human	View/Edit Mouse

Keratin 12 is a protein that in humans is encoded by the KRT12 gene. It is a type I keratin.

Keratin 12 is keratin found expressed in corneal epithelia. Mutations in the gene encoding this protein lead to Meesmann corneal dystrophy.