KRT33B

KRT33B
Identifiers
Aliases	KRT33B, HA3II, Ha-3II, K33B, KRTHA3A, KRTHA3B, hHa3-II, keratin 33B
External IDs	OMIM: 602762; MGI: 1919138; HomoloGene: 136754; GeneCards: KRT33B; OMA:KRT33B - orthologs
Gene location (Human)
Chr.	Chromosome 17 (human)
End	41,369,813 bp
Gene location (Mouse)
Chr.	Chromosome 11 (mouse)
End	99,907,038 bp
RNA expression pattern
	Top expressed in
	prefrontal cortex; ; anterior cingulate cortex; ; skin of abdomen; ; skin of leg; ; Brodmann area 9; ; right lung; ; mucosa of esophagus; ; right frontal lobe; ; vagina; ; hippocampus proper;
	Top expressed in
	lip; ; hair follicle; ; skin of back; ; dermis; ; skin of external ear; ; skin of abdomen; ; sexually immature organism; ; medial head of gastrocnemius muscle; ; conjunctival fornix; ; diencephalon;
	More reference expression data
	More reference expression data
Gene ontology
Molecular function	protein binding; structural molecule activity;
Cellular component	extracellular exosome; intermediate filament; extracellular space; cytosol;
Biological process	hair cycle; ageing; keratinization; cornification;
	Sources:Amigo / QuickGO
Orthologs
	3884
	71888
	ENSG00000263012; ENSG00000131738
	ENSMUSG00000035592
	Q14525
	Q8K0Y2
	NM_002279
	NM_027983
	NP_002270
	NP_082259
	Wikidata
View/Edit Human	View/Edit Mouse

Keratin, type I cuticular Ha3-II is a protein that in humans is encoded by the KRT33B gene.

The protein encoded by this gene is a member of the keratin gene family. It is one of the type I hair keratin genes which are clustered in a region of chromosome 17q21.2 and have the same direction of transcription. As a type I hair keratin, it is an acidic protein which heterodimerizes with type II hair keratin to form hair and nails. There are two isoforms of this protein, encoded by two separate genes, KRT33A and KRT33B (this gene).