Keratin 6A

KRT6A
Identifiers
Aliases	KRT6A, CK6A, CK6C, CK6D, K6A, K6C, K6D, KRT6C, KRT6D, PC3, CK-6C, CK-6E, keratin 6A
External IDs	OMIM: 148041; MGI: 1333768; HomoloGene: 36182; GeneCards: KRT6A; OMA:KRT6A - orthologs
Gene location (Human)
Chr.	Chromosome 12 (human)
End	52,493,257 bp
Gene location (Mouse)
Chr.	Chromosome 15 (mouse)
End	101,588,722 bp
RNA expression pattern
	Top expressed in
	gingival epithelium; ; amniotic fluid; ; hair follicle; ; vulva; ; body of tongue; ; oral cavity; ; mucosa of pharynx; ; human penis; ; skin of arm; ; skin of thigh;
	Top expressed in
	conjunctival fornix; ; ciliary body; ; corneal stroma; ; cervix; ; retinal pigment epithelium; ; epithelium of lens; ; lip; ; umbilical cord; ; iris; ; sexually immature organism;
	More reference expression data
	n/a
Gene ontology
Molecular function	structural constituent of cytoskeleton; protein binding; structural molecule activity;
Cellular component	keratin filament; extracellular exosome; intermediate filament; membrane; nucleus; cytosol;
Biological process	morphogenesis of an epithelium; cell differentiation; wound healing; positive regulation of cell population proliferation; cytoskeleton organization; keratinization; cornification; negative regulation of cytolysis by symbiont of host cells; negative regulation of entry of bacterium into host cell;
	Sources:Amigo / QuickGO
Orthologs
	3853
	16688
	ENSG00000205420
	ENSMUSG00000023041
	P02538
	Q9Z331; Q3UV11
	NM_005554
	NM_010669
	NP_005545
	NP_034799
	Wikidata
View/Edit Human	View/Edit Mouse

Keratin 6A is one of the 27 different type II keratins expressed in humans. Keratin 6A was the first type II keratin sequence determined. Analysis of the sequence of this keratin together with that of the first type I keratin led to the discovery of the four helical domains in the central rod of keratins. In humans Keratin 6A is encoded by the KRT6A gene.