KSR1

KSR1
Available structures
PDB	Ortholog search: PDBe RCSB
List of PDB id codes
	1KBE, 1KBF, 2LPE
Identifiers
Aliases	KSR1, KSR, RSU2, kinase suppressor of ras 1
External IDs	OMIM: 601132; MGI: 105051; HomoloGene: 8410; GeneCards: KSR1; OMA:KSR1 - orthologs
Gene location (Human)
Chr.	Chromosome 17 (human)
End	27,626,438 bp
Gene location (Mouse)
Chr.	Chromosome 11 (mouse)
End	79,037,233 bp
RNA expression pattern
	Top expressed in
	body of pancreas; ; sural nerve; ; oocyte; ; right lobe of thyroid gland; ; canal of the cervix; ; left lobe of thyroid gland; ; gallbladder; ; ectocervix; ; left testis; ; left ovary;
	Top expressed in
	muscle of thigh; ; temporal muscle; ; triceps brachii muscle; ; dentate gyrus of hippocampal formation granule cell; ; digastric muscle; ; medial head of gastrocnemius muscle; ; sternocleidomastoid muscle; ; quadriceps femoris muscle; ; granulocyte; ; vastus lateralis muscle;
	More reference expression data
	; ;
	More reference expression data
Gene ontology
Molecular function	metal ion binding; protein C-terminus binding; protein binding; ATP binding; MAP-kinase scaffold activity; protein kinase activity; signal transducer activity; mitogen-activated protein kinase kinase binding; chaperone binding; Hsp90 protein binding; 14-3-3 protein binding;
Cellular component	cytoplasm; cytosol; endoplasmic reticulum membrane; membrane; endoplasmic reticulum; cell projection; ruffle membrane; plasma membrane; protein-containing complex;
Biological process	intracellular signal transduction; MAPK cascade; cAMP-mediated signaling; protein phosphorylation; Ras protein signal transduction; positive regulation of MAPK cascade; regulation of cell population proliferation; regulation of MAP kinase activity;
	Sources:Amigo / QuickGO
Orthologs
	8844
	16706
	ENSG00000141068
	ENSMUSG00000018334
	Q8IVT5
	Q61097
	NM_014238; NM_001367810; NM_001394583; NM_001394584; NM_001394585
	NM_013571; NM_001348207
	NP_055053; NP_001354739
	NP_001335136; NP_038599
	Wikidata
View/Edit Human	View/Edit Mouse

Kinase suppressor of Ras 1 is an enzyme that in humans is encoded by the KSR1 gene.