Knorr pyrrole synthesis

Knorr pyrrole synthesis
Named after Ludwig Knorr
Reaction type Ring forming reaction
Identifiers
RSC ontology ID RXNO:0000497

The Knorr pyrrole synthesis is a widely used chemical reaction that synthesizes substituted pyrroles (3). The method involves the reaction of an α-amino-ketone (1) and a compound containing an electron-withdrawing group (e.g. an ester as shown) α to a carbonyl group (2).

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