MAP2K1IP1

LAMTOR3
Available structures
PDB	Ortholog search: PDBe RCSB
List of PDB id codes
	1SKO, 2ZL1, 3CPT
Identifiers
Aliases	LAMTOR3, MAP2K1IP1, MAPBP, MAPKSP1, MP1, PRO0633, Ragulator3, late endosomal/lysosomal adaptor, MAPK and MTOR activator 3
External IDs	OMIM: 603296; MGI: 1929467; HomoloGene: 10539; GeneCards: LAMTOR3; OMA:LAMTOR3 - orthologs
Gene location (Human)
Chr.	Chromosome 4 (human)
End	99,894,428 bp
Gene location (Mouse)
Chr.	Chromosome 3 (mouse)
End	137,634,661 bp
RNA expression pattern
	Top expressed in
	mucosa of sigmoid colon; ; oocyte; ; retinal pigment epithelium; ; ventricular zone; ; islet of Langerhans; ; Achilles tendon; ; secondary oocyte; ; palpebral conjunctiva; ; rectum; ; ganglionic eminence;
	Top expressed in
	fossa; ; facial motor nucleus; ; secondary oocyte; ; condyle; ; renal corpuscle; ; medullary collecting duct; ; trigeminal ganglion; ; atrioventricular junction; ; vestibular membrane of cochlear duct; ; Paneth cell;
	More reference expression data
	More reference expression data
Gene ontology
Molecular function	guanyl-nucleotide exchange factor activity; protein binding; molecular adaptor activity; kinase activator activity;
Cellular component	endosome; membrane; late endosome membrane; focal adhesion; Ragulator complex; lysosomal membrane; endosome membrane; extracellular exosome; late endosome; plasma membrane; specific granule membrane; tertiary granule membrane;
Biological process	regulation of TOR signaling; MAPK cascade; cellular response to amino acid stimulus; positive regulation of TOR signaling; neutrophil degranulation; regulation of macroautophagy;
	Sources:Amigo / QuickGO
Orthologs
	8649
	56692
	ENSG00000109270
	ENSMUSG00000091512
	Q9UHA4
	O88653
	NM_001243736; NM_021970
	NM_019920
	NP_001230665; NP_068805
	NP_064304
	Wikidata
View/Edit Human	View/Edit Mouse

Mitogen-activated protein kinase scaffold protein 1 is a scaffold protein that in humans is encoded by the MAPKSP1 gene.